Wednesday, October 16, 2013

Alzheimer’s Disease Stages – Mild, Moderate & Severe


The neurological hallmarks of Alzheimer’s Disease, neurofibrillary plaques and tangles, develop in the brain long before symptoms are apparent. Often times, people delay seeing a doctor and the possibility of hearing that the diagnosis could be Alzheimer’s Disease. When an evaluation is delayed, symptoms may be more progressed at the time of diagnosis, limiting treatment and intervention options. 

The stages of Alzheimer’s Disease may be conceptualized in three general categories:
  1. Mild Alzheimer’s Disease: during this stage, mild changes in memory loss and thinking occur. This oftentimes is confused with the natural progression of aging. Another symptom that may be apparent in this stage is the inability to judge time. This includes knowing how much time is needed to complete a task, knowing how long it takes to get from one place to another, etc. Some individuals tend to get lost or misplace things, have a change in personality, difficulty with problem solving, and/or difficulty expressing and organizing their thoughts.
  2. Moderate Alzheimer’s Disease: during this stage, memory loss gradually worsens and the affected person starts to need help with basic daily activities including: grooming, using the restroom, etc. More behavior and personality changes are present.  Family and friends start to explicitly see the effects of Alzheimer’s because the individual may confuse family members and friends with strangers they have never met. It can be unsafe to leave an individual suffering from moderate Alzheimer’s Disease on their own without any close care.
  3. Severe Alzheimer’s Disease: during this stage, the individual living with Alzheimer’s Disease is completely dependent on their caregiver. People lose their verbal language ability, which sometimes leads to complete loss of speech. Muscle mass starts to deteriorate and some even lose the ability to feed themselves. In the most severe cases of Alzheimer’s Disease, this terminal illness leads to death.
On average, people with Alzheimer’s Disease can live anywhere from 8-10 years from the time of diagnosis, and some may live up to 25 years. If you or a loved one are experiencing symptoms of Alzheimer’s Disease, please schedule an evaluation.

For information on clinical research for memory loss and Alzheimer’s Disease, please visit http://www.thecrcnj.com/CurrentStudies.html.


Wednesday, October 2, 2013

Alzheimer’s Disease – Symptoms, Causes & Risk Factors


Since the changes in the brain that occur in Alzheimer’s Disease (AD) are known to develop years before symptoms present themselves, it is critical to identify signs of Alzheimer’s early on in order to try and discover interventions that may be beneficial. Some symptoms of Alzheimer’s Disease may be difficult to detect at first because changes in thinking skills, such as forgetfulness or an occasional loss of focus, also occur in normal aging. However, with Alzheimer’s Disease, symptoms progress to interfere with everyday functioning.

Here are some early warning signs and potential symptoms of Alzheimer’s Disease:
  1. Planning and Managing Problems: Have you or a loved one noticed that routine tasks, such as paying bills or writing a to-do list, have become difficult?
  2. Speaking and Writing: Do you or a loved one have trouble expressing your thoughts, or do you find it difficult to find the right words to identify objects? Do you have trouble reading or writing?
  3. Confusion with Time or Place: Do you or a loved one lose track of dates, time or even seasons? Do you ever find yourself forgetting where you are or how you got there?
  4. Misplacing Items: Do you or a loved one misplace things, finding it difficult to retrace your steps in order to find the missing item? Do you ever accuse others of stealing your personal belongings?
  5. Changes in Mood, Personality or Behavior: Do you or a loved one find yourself feeling confused, depressed, anxious or fearful? When you feel out of your comfort zone, do you find yourself becoming more easily upset? Do you wander? Do you have a change in your sleeping habits?
In Alzheimer’s Disease, brain cells are affected by neurofibrillary plaques and tangles, which cause cell death and interfere with brain activity. The downstream results are a decline in thinking skills and behavior. The rate at which these changes occur varies from one individual to another.

Symptoms of memory loss or other changes in thinking skills or personality should not be taken lightly.  The best course of action is to seek an evaluation to determine the cause and course of action for managing symptoms.

If you or a loved one is concerned about such symptoms, or has a diagnosis of Alzheimer’s Disease, and are interested in learning more about clinical research, please visit http://www.thecrcnj.com/CurrentStudies.html.